| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 22-Aug-2021 | draw |  Clermont Foot | 3-3 | home |
| 27-Aug-2021 | win |  FC Nantes | 0-1 | away |
| 12-Sep-2021 | win | RC Strasbourg | 3-1 | home |
| 19-Sep-2021 | lose |  Paris Saint-Germain | 2-1 | away |
| 03-Oct-2021 | draw |  AS Saint-Etienne | 1-1 | away |
| 16-Oct-2021 | win |  AS Monaco | 2-0 | home |
| 24-Oct-2021 | lose |  OGC Nice | 3-2 | away |
| 30-Oct-2021 | win | RC Lens | 2-1 | home |
| 28-Nov-2021 | win |  Montpellier HSC | 0-1 | away |
| 05-Dec-2021 | draw |  Girondins De Bordeaux | 2-2 | away |
| 22-Dec-2021 | draw |  FC Metz | 1-1 | home |
| 09-Jan-2022 | draw | Paris Saint-Germain | 1-1 | home |
| 16-Jan-2022 | win | Troyes AC | 0-1 | away |
| 21-Jan-2022 | win | AS Saint-Etienne | 1-0 | home |
| 12-Feb-2022 | win | OGC Nice | 2-0 | home |
| 04-Mar-2022 | win |  FC Lorient | 1-4 | away |
| 03-Apr-2022 | win |  Angers SCO | 3-2 | home |
| 17-Apr-2022 | win | Girondins De Bordeaux | 6-1 | home |
| 23-Apr-2022 | win | Montpellier HSC | 5-2 | home |
| 01-May-2022 | win |  Olympique Marseille | 0-3 | away |
| 14-May-2022 | win | FC Nantes | 3-2 | home |
| 21-May-2022 | win | Clermont Foot | 1-2 | away |
Overall ( 15 wins,5 draw,2 lost )
Home ( 9 wins,3 draw,0 lost )
Away ( 6 wins,2 draw,2 lost )
OPP = Opposition,
FS = Final score.