| 4 | Paolo Cannavaro | Group Stage | UEFA Champions League 11/12 |
| 3 | Min-Jae Kim | Group Stage | UEFA Champions League 22/23 |
| 3 | Kalidou Koulibaly | Group Stage | UEFA Champions League 17/18 |
| 3 | Dries Mertens | Group Stage | UEFA Champions League 17/18 |
| 3 | Federico Fernandez | Group Stage | UEFA Champions League 13/14 |
| 2 | Juan | Group Stage | UEFA Champions League 22/23 |
| 2 | Amir Rrahmani | Group Stage | UEFA Champions League 22/23 |
| 2 | Matteo Politano | Group Stage | UEFA Champions League 22/23 |
| 2 | Frank Anguissa | Quarter-finals | UEFA Champions League 22/23 |
| 2 | Giovanni Di Lorenzo | Quarter-finals | UEFA Champions League 22/23 |
| 2 | Piotr Zielinski | Group Stage | UEFA Champions League 19/20 |
| 2 | Kalidou Koulibaly | Group Stage | UEFA Champions League 19/20 |
| 2 | Fernando Llorente | Group Stage | UEFA Champions League 19/20 |
| 2 | Mario Rui | Group Stage | UEFA Champions League 19/20 |
| 2 | Kalidou Koulibaly | Group Stage | UEFA Champions League 18/19 |
| 2 | Christian Maggio | Group Stage | UEFA Champions League 17/18 |
| 2 | Kalidou Koulibaly | Group Stage | UEFA Champions League 16/17 |
| 2 | Juan | Group Section | UEFA Champions League 23/24 |
| 2 | Mathias Olivera | Group Section | UEFA Champions League 23/24 |
| 2 | Ezequiel Ivan Lavezzi | Group Stage | UEFA Champions League 11/12 |
| 2 | Christian Maggio | Group Stage | UEFA Champions League 11/12 |
| 2 | Camilo Zuniga | Group Stage | UEFA Champions League 11/12 |
| 2 | Hugo Campagnaro | Group Stage | UEFA Champions League 11/12 |
| 2 | Gokhan Inler | Group Stage | UEFA Champions League 11/12 |
| 2 | Salvatore Aronica | Group Stage | UEFA Champions League 11/12 |
| 2 | Edinson Cavani | Group Stage | UEFA Champions League 11/12 |
| 1 | Elif Elmas | Round of 16 | UEFA Champions League 22/23 |
| 1 | Mathias Olivera | Quarter-finals | UEFA Champions League 22/23 |
| 1 | Victor Osimhen | Group Stage | UEFA Champions League 22/23 |
| 1 | Piotr Zielinski | Quarter-finals | UEFA Champions League 22/23 |
| 1 | Mario Rui | Group Stage | UEFA Champions League 22/23 |
| 1 | Giacomo Raspadori | Group Stage | UEFA Champions League 22/23 |
| 1 | Arkadiusz Milik | Group Stage | UEFA Champions League 19/20 |
| 1 | Lorenzo Insigne | Round of 16 | UEFA Champions League 19/20 |
| 1 | Fabian | Group Stage | UEFA Champions League 19/20 |
| 1 | Kevin Malcuit | Group Stage | UEFA Champions League 19/20 |
| 1 | Allan | Group Stage | UEFA Champions League 19/20 |
| 1 | Hirving Lozano | Group Stage | UEFA Champions League 19/20 |
| 1 | Raul Albiol | Group Stage | UEFA Champions League 18/19 |
| 1 | Allan | Group Stage | UEFA Champions League 18/19 |
| 1 | Fabian | Group Stage | UEFA Champions League 18/19 |
| 1 | Arkadiusz Milik | Group Stage | UEFA Champions League 18/19 |
| 1 | Elseid Hysaj | Group Stage | UEFA Champions League 18/19 |
| 1 | Mario Rui | Group Stage | UEFA Champions League 18/19 |
| 1 | Lorenzo Insigne | Group Stage | UEFA Champions League 17/18 |
| 1 | Raul Albiol | Group Stage | UEFA Champions League 17/18 |
| 1 | Pepe Reina | Group Stage | UEFA Champions League 17/18 |
| 1 | Amadou Diawara | Group Stage | UEFA Champions League 17/18 |
| 1 | Vlad Chiriches | Group Stage | UEFA Champions League 17/18 |
| 1 | Pepe Reina | Group Stage | UEFA Champions League 16/17 |
| 1 | Piotr Zielinski | Round of 16 | UEFA Champions League 16/17 |
| 1 | Christian Maggio | Group Stage | UEFA Champions League 16/17 |
| 1 | Dries Mertens | Round of 16 | UEFA Champions League 16/17 |
| 1 | Jorginho | Group Stage | UEFA Champions League 16/17 |
| 1 | Allan | Round of 16 | UEFA Champions League 16/17 |
| 1 | Arkadiusz Milik | Group Stage | UEFA Champions League 16/17 |
| 1 | Amadou Diawara | Round of 16 | UEFA Champions League 16/17 |
| 1 | Victor Osimhen | Group Section | UEFA Champions League 23/24 |
| 1 | Amir Rrahmani | Group Section | UEFA Champions League 23/24 |
| 1 | Hamed Junior Traore | Round of 16 | UEFA Champions League 23/24 |
