| 5 | Sergio Ramos | Group Stage | UEFA Champions League 12/13 |
| 5 | Ivan Helguera | First Group Stage | UEFA Champions League 00/01 |
| 4 | Eder Militao | Group Stage | UEFA Champions League 21/22 |
| 4 | Casemiro | Group Stage | UEFA Champions League 20/21 |
| 4 | Daniel Carvajal | Group Stage | UEFA Champions League 17/18 |
| 4 | Sergio Ramos | Group Stage | UEFA Champions League 16/17 |
| 4 | Marcelo | Group Stage | UEFA Champions League 14/15 |
| 4 | Sergio Ramos | Group Stage | UEFA Champions League 14/15 |
| 4 | Xabi Alonso | Group Stage | UEFA Champions League 11/12 |
| 4 | Sergio Ramos | Group Stage | UEFA Champions League 10/11 |
| 4 | Ricardo Carvalho | Group Stage | UEFA Champions League 10/11 |
| 4 | Sergio Ramos | Group Stage | UEFA Champions League 06/07 |
| 4 | Guti | Group Stage | UEFA Champions League 05/06 |
| 4 | Michel Salgado | Final | UEFA Champions League 99/00 |
| 4 | Ivan Helguera | First Group Stage | UEFA Champions League 01/02 |
| 4 | Luis Figo | First Group Stage | UEFA Champions League 00/01 |
| 3 | Daniel Carvajal | Group Stage | UEFA Champions League 22/23 |
| 3 | Eduardo Camavinga | Quarter-finals | UEFA Champions League 22/23 |
| 3 | Daniel Carvajal | Round of 16 | UEFA Champions League 21/22 |
| 3 | Casemiro | Group Stage | UEFA Champions League 21/22 |
| 3 | Ferland Mendy | Group Stage | UEFA Champions League 21/22 |
| 3 | Federico Valverde | Group Stage | UEFA Champions League 20/21 |
| 3 | Toni Kroos | Round of 16 | UEFA Champions League 20/21 |
| 3 | Luka Modric | Group Stage | UEFA Champions League 19/20 |
| 3 | Sergio Ramos | Group Stage | UEFA Champions League 18/19 |
| 3 | Sergio Ramos | Group Stage | UEFA Champions League 17/18 |
| 3 | Toni Kroos | Group Stage | UEFA Champions League 16/17 |
| 3 | Casemiro | Group Stage | UEFA Champions League 15/16 |
| 3 | Sergio Ramos | Group Stage | UEFA Champions League 15/16 |
| 3 | Daniel Carvajal | Group Stage | UEFA Champions League 15/16 |
| 3 | Danilo | Group Stage | UEFA Champions League 15/16 |
| 3 | Daniel Carvajal | Round of 16 | UEFA Champions League 23/24 |
| 3 | James Rodriguez | Group Stage | UEFA Champions League 14/15 |
| 3 | Sergio Ramos | Group Stage | UEFA Champions League 13/14 |
| 3 | Luka Modric | Group Stage | UEFA Champions League 13/14 |
| 3 | Alvaro Arbeloa | Group Stage | UEFA Champions League 12/13 |
| 3 | Xabi Alonso | Group Stage | UEFA Champions League 12/13 |
| 3 | Xabi Alonso | Group Stage | UEFA Champions League 10/11 |
| 3 | Pepe | Group Stage | UEFA Champions League 10/11 |
| 3 | Emmanuel Adebayor | Quarter-finals | UEFA Champions League 10/11 |
| 3 | Xabi Alonso | Group Stage | UEFA Champions League 09/10 |
| 3 | Marcelo | Group Stage | UEFA Champions League 09/10 |
| 3 | Manolo Sanchis | Quarter-finals | UEFA Champions League 98/99 |
| 3 | Fernando Hierro | Final | UEFA Champions League 97/98 |
| 3 | Roberto Carlos | Final | UEFA Champions League 97/98 |
| 3 | Sergio Ramos | Group Stage | UEFA Champions League 07/08 |
| 3 | Pablo Garcia | Group Stage | UEFA Champions League 05/06 |
| 3 | Walter Samuel | Group Stage | UEFA Champions League 04/05 |
| 3 | David Beckham | Group Stage | UEFA Champions League 03/04 |
| 3 | Roberto Carlos | First Group Stage | UEFA Champions League 02/03 |
| 3 | Ivan Helguera | First Group Stage | UEFA Champions League 02/03 |
| 3 | Roberto Carlos | Final | UEFA Champions League 99/00 |
| 3 | Aitor Karanka | Semi-finals | UEFA Champions League 99/00 |
| 3 | Pedro Munitis | Second Group Stage | UEFA Champions League 01/02 |
| 3 | Luis Figo | First Group Stage | UEFA Champions League 01/02 |
| 3 | Fernando Hierro | Second Group Stage | UEFA Champions League 00/01 |
| 2 | Toni Kroos | Group Stage | UEFA Champions League 22/23 |
| 2 | Eder Militao | Quarter-finals | UEFA Champions League 22/23 |
| 2 | Luka Modric | Group Stage | UEFA Champions League 21/22 |
| 2 | Nacho | Round of 16 | UEFA Champions League 21/22 |
