| DOB | Players | Clubs | Nationality | SD | A(D) | More |
|---|---|---|---|---|---|---|
| 27-Mar-2004 |  Quinn Sullivan | Philadelphia Union | United States | 27-Jun-2021 | 17(91) | |
| 14-Oct-2003 | Cade Cowell | San Jose Earthquakes | United States | 24-Apr-2021 | 17(192) | |
| 27-May-2003 | Caden Clark | New York Red Bulls | United States | 18-Apr-2021 | 17(325) | |
| 26-Aug-2003 | Paxten Aaronson | Philadelphia Union | United States | 08-Aug-2021 | 17(347) | |
| 07-Apr-2003 | Dante Sealy | FC Dallas | United States | 02-May-2021 | 18(24) | |
| 07-May-2003 | Kevin Paredes | DC United | Peru | 03-Jul-2021 | 18(55) | |
| 09-Jan-2003 | Ricardo Pepi | FC Dallas | United States | 24-Apr-2021 | 18(105) | |
| 24-Feb-2003 | Wikelman Carmona | New York Red Bulls | Venezuela | 31-Jul-2021 | 18(158) | |
| 25-Sep-2002 | Griffin Yow | DC United | United States | 03-Jul-2021 | 18(281) | |
| 01-Oct-2002 | Ibrahim Sunusi | Montreal Impact | Nigeria | 15-Aug-2021 | 18(317) | |
| 28-May-2002 | Ganluca Busio | Sporting Kansas City | United States | 24-Apr-2021 | 18(330) | |
| 02-Aug-2002 | Ralph Priso-Mbongue | Toronto FC | Canada | 22-Jul-2021 | 18(354) | |
| 19-Jun-2002 | Efrain Alvarez | Los Angeles Galaxy | Mexico | 24-Jun-2021 | 19(4) | |
| 31-Jul-2002 | John Tolkin | New York Red Bulls | United States | 19-Aug-2021 | 19(18) | |
| 27-Nov-2001 | Erik Lopez | Atlanta United | Paraguay | 29-May-2021 | 19(184) | |
| 03-Dec-2001 | Jackson Conway | Atlanta United | England | 09-Jul-2021 | 19(218) | |
| 28-Jul-2001 | Cole Bassett | Colorado Rapids | United States | 09-May-2021 | 19(284) | |
| 13-Feb-2001 | Cameron Duke | Sporting Kansas City | United States | 26-Jul-2021 | 20(164) | |
| 16-Feb-2001 | Indiana Vassilev | Inter Miami CF | United States | 08-Aug-2021 | 20(174) | |
| 24-Dec-2000 | Jesus Ferreira | FC Dallas | United States | 01-Aug-2021 | 20(220) | |
| 27-Sep-2000 | Frankie Amaya | New York Red Bulls | United States | 08-May-2021 | 20(223) | |
| 30-Oct-2000 | Thiago | New York City | Brazil | 20-Jun-2021 | 20(233) | |
| 14-Nov-2000 | Andres Perea | Orlando City | Colombia | 08-Jul-2021 | 20(236) | |
| 17-Aug-2000 | Alvaro Barreal | Cincinnati | Argentina | 16-May-2021 | 20(271) | |
| 06-Oct-2000 | Braian Galvan | Colorado Rapids | Argentina | 08-Jul-2021 | 20(275) | |
| 03-Jun-2000 | Daryl Dike | Orlando City | United States | 23-Jun-2021 | 21(19) | |
| 27-May-2000 | Chinonso Offor | Chicago Fire | Nigeria | 08-Jul-2021 | 21(40) | |
| 27-Mar-2000 | Jaylin Lindsey | Sporting Kansas City | United States | 23-May-2021 | 21(55) | |
| 25-Mar-2000 | Deiber Caicedo | Vancouver Whitecaps | Colombia | 23-May-2021 | 21(57) | |
| 12-Feb-2000 | Luke Singh | Toronto FC | Trinidad and Tobago | 24-Apr-2021 | 21(72) |
SD = Scored Date ,
DOB = Date Of Birth ,
A(D) = Age(Days) .