| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Guglielmo Vicario | Empoli | Italy | 73 | |
| 2 | Andrea Consigli | Sassuolo | Italy | 67 | |
| 3 | Alessio Cragno | Cagliari | Italy | 63 | |
| 4 | Salvatore Sirigu | Genoa | Italy | 60 | |
| 5 | Ivan Provedel | Spezia Calcio | Italy | 55 | |
| 6 | Lukasz Skorupski | Bologna | Poland | 54 | |
| 7 | Emil Audero | Sampdoria | Italy | 53 | |
| 8 | Marco Silvestri | Udinese | Italy | 52 | |
| 9 | Lorenzo Montipo | Hellas Verona | Italy | 52 | |
| 10 | Vid Belec | Salernitana | Slovenia | 50 | |
| 11 | Juan Musso | Atalanta | Argentina | 46 | |
| 12 | Rui Patricio | AS Roma | Portugal | 44 | |
| 13 | Pietro Terracciano | Fiorentina | Italy | 40 | |
| 14 | Vanja Milinkovic-Savic | Torino | Serbia | 36 | |
| 15 | Sergio Romero | Venezia | Argentina | 33 | |
| 16 | Thomas Strakosha | SS Lazio | Albania | 32 | |
| 17 | Samir Handanovic | Internazionale | Slovenia | 31 | |
| 18 | Wojciech Szczesny | Juventus | Poland | 30 | |
| 19 | Pepe Reina | SS Lazio | Spain | 29 | |
| 20 | Nikki Maenpaa | Venezia | Finland | 26 |
GC = Goals conceded