| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Alex Cordaz | FC Crotone | Italy | 92 | |
| 2 | Luigi Sepe | Parma | Italy | 76 | |
| 3 | Lorenzo Montipo | Benevento | Italy | 74 | |
| 4 | Salvatore Sirigu | Torino | Italy | 63 | |
| 5 | Bartlomiej Dragowski | Fiorentina | Poland | 60 | |
| 6 | Andrea Consigli | Sassuolo | Italy | 59 | |
| 7 | Ivan Provedel | Spezia Calcio | Italy | 55 | |
| 8 | Emil Audero | Sampdoria | Italy | 54 | |
| 9 | Alessio Cragno | Cagliari | Italy | 53 | |
| 10 | Juan Musso | Udinese | Argentina | 52 | |
| 11 | Lukasz Skorupski | Bologna | Poland | 47 | |
| 12 | Mattia Perin | Genoa | Italy | 45 | |
| 13 | Marco Silvestri | Hellas Verona | Italy | 45 | |
| 14 | Pepe Reina | SS Lazio | Spain | 43 | |
| 15 | Gianluigi Donnarumma | AC Milan | Italy | 40 | |
| 16 | Samir Handanovic | Internazionale | Slovenia | 39 | |
| 17 | Wojciech Szczesny | Juventus | Poland | 34 | |
| 18 | Alex Meret | Napoli | Italy | 32 | |
| 19 | Pierluigi Gollini | Atalanta | Italy | 29 | |
| 20 | Pau Lopez | AS Roma | Spain | 29 |
GC = Goals conceded