| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Jordan Ayew | 38 | 31 | 7 | 7 | 14 | 4 |
Eberechi Eze | 38 | 30 | 8 | 8 | 15 | 10 |
Marc Guehi | 37 | 37 | - | - | 1 | 1 |
Michael Olise | 37 | 31 | 6 | 6 | 14 | 2 |
Tyrick Mitchell | 36 | 34 | 2 | 2 | 6 | - |
Odsonne Edouard | 35 | 20 | 17 | 15 | 18 | 5 |
Cheick Doucoure | 34 | 34 | 1 | - | 17 | - |
Jeffrey Schlupp | 34 | 30 | 4 | 4 | 19 | 3 |
Joachim Andersen | 32 | 32 | - | - | 2 | 1 |
Jean Philippe Mateta | 29 | 6 | 31 | 23 | 6 | 2 |
Joel Ward | 28 | 24 | 11 | 4 | 2 | 1 |
Wilfred Zaha | 27 | 27 | - | - | 6 | 7 |
Vicente Guaita | 27 | 27 | 5 | - | - | - |
Will Hughes | 27 | 7 | 26 | 20 | 6 | 1 |
Nathaniel Clyne | 22 | 19 | 11 | 3 | 5 | - |
Luka Milivojevic | 18 | 5 | 29 | 13 | 4 | - |
Sam Johnstone | 9 | 9 | 21 | - | - | - |
Albert Sambi Lokonga | 9 | 6 | 11 | 3 | 3 | - |
Chris Richards | 9 | 4 | 23 | 5 | - | - |
Naouirou Ahamada | 8 | - | 11 | 8 | - | - |
James Tomkins | 6 | 3 | 19 | 3 | - | 1 |
Jairo Riedewald | 6 | - | 30 | 6 | - | - |
James McArthur | 4 | - | 12 | 4 | - | - |
Malcolm Ebiowei | 3 | - | 17 | 3 | - | - |
Joe Whitworth | 2 | 2 | 12 | - | - | - |
David Ozoh | 1 | - | 4 | 1 | - | - |
Luke Plange | - | - | 2 | - | - | - |
Kofi Balmer | - | - | 3 | - | - | - |
Jack Wells-Morrison | - | - | 2 | - | - | - |
Owen Goodman | - | - | 4 | - | - | - |
Tayo Adaramola | - | - | 2 | - | - | - |
Jack Butland | - | - | 2 | - | - | - |
Killian Phillips | - | - | 2 | - | - | - |
John-Kymani Gordon | - | - | 5 | - | - | - |
Kaden Rodney | - | - | 2 | - | - | - | 556 | 418 | 342 | 138 | 138 | 38 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .