| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Timo Horn | 34 | 34 | - | - | 1 | - |
Ondrej Duda | 32 | 32 | - | - | 18 | 7 |
Ellyes Skhiri | 32 | 32 | 1 | - | 6 | 5 |
Marius Wolf | 31 | 29 | 2 | 2 | 11 | 2 |
Elvis Rexhbecaj | 30 | 20 | 13 | 10 | 12 | 5 |
Jannes Horn | 29 | 20 | 13 | 9 | 8 | - |
Rafael Czichos | 28 | 26 | 2 | 2 | 5 | 1 |
Salih Ozcan | 28 | 15 | 19 | 13 | 8 | - |
Dominic Drexler | 27 | 11 | 23 | 16 | 8 | 2 |
Sebastiaan Bornauw | 24 | 23 | 2 | 1 | - | 1 |
Jan Thielmann | 24 | 9 | 19 | 15 | 7 | 2 |
Ismail Jakobs | 23 | 18 | 6 | 5 | 6 | 1 |
Kingsley Ehizibue | 21 | 15 | 16 | 6 | 13 | - |
Noah Katterbach | 21 | 12 | 20 | 9 | 7 | - |
Jonas Hector | 19 | 15 | 5 | 4 | 8 | 3 |
Jorge Mere | 16 | 14 | 14 | 2 | 2 | - |
Sebastian Andersson | 16 | 14 | 3 | 2 | 9 | 3 |
Benno Schmitz | 12 | 4 | 22 | 8 | 2 | - |
Dimitris Limnios | 12 | 2 | 19 | 10 | 2 | - |
Sava-Arangel Cestic | 11 | 11 | 6 | - | 2 | - |
Max Meyer | 10 | 3 | 13 | 7 | - | - |
Emmanuel Dennis | 9 | 6 | 6 | 3 | 4 | - |
Toluwalase Arokodare | 9 | - | 17 | 9 | - | - |
Florian Kainz | 8 | 6 | 2 | 2 | 5 | 1 |
Anthony Modeste | 7 | 1 | 12 | 6 | 1 | - |
Frederik Sorensen | 3 | 1 | 7 | 2 | - | - |
Marco Hoger | 3 | 1 | 5 | 2 | 1 | - |
Ron-Robert Zieler | 1 | - | 34 | 1 | - | - |
Marvin Obuz | - | - | 1 | - | - | - |
Tim Lemperle | - | - | 2 | - | - | - | 520 | 374 | 304 | 146 | 146 | 33 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .