| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Harry Maguire | 26 | 26 | - | - | - | 2 |
Bruno Fernandes | 26 | 25 | 1 | 1 | 9 | 15 |
Marcus Rashford | 26 | 24 | 2 | 2 | 6 | 9 |
David De Gea | 24 | 24 | 1 | - | 1 | - |
Aaron Wan-Bissaka | 24 | 24 | 1 | - | - | 2 |
Luke Shaw | 22 | 20 | 3 | 2 | 3 | - |
Scott McTominay | 22 | 16 | 8 | 6 | 3 | 4 |
Anthony Martial | 21 | 16 | 6 | 5 | 10 | 4 |
Victor Lindelof | 20 | 20 | 2 | - | 1 | 1 |
Fred | 20 | 17 | 8 | 3 | 5 | - |
Mason Greenwood | 20 | 13 | 10 | 7 | 11 | 1 |
Paul Pogba | 19 | 15 | 6 | 4 | 3 | 3 |
Edinson Cavani | 17 | 8 | 9 | 9 | 2 | 6 |
Nemanja Matic | 13 | 9 | 16 | 4 | 1 | - |
Donny van de Beek | 13 | 2 | 23 | 11 | 1 | 1 |
Daniel James | 9 | 7 | 13 | 2 | 5 | 3 |
Eric Bailly | 7 | 6 | 11 | 1 | - | - |
Alex Telles | 7 | 6 | 14 | 1 | 3 | - |
Juan Mata | 7 | 4 | 14 | 3 | 4 | - |
Axel Tuanzebe | 6 | 1 | 17 | 5 | 1 | - |
Dean Henderson | 3 | 2 | 24 | 1 | - | - |
Timothy Fosu-Mensah | 1 | 1 | 2 | - | 1 | - |
Odion Ighalo | 1 | - | 2 | 1 | - | - |
Brandon Williams | 1 | - | 9 | 1 | - | - |
Shola Shoretire | 1 | - | 1 | 1 | - | - |
Jesse Lingard | - | - | 4 | - | - | - |
Amad Diallo | - | - | 2 | - | - | - |
Lee Grant | - | - | 1 | - | - | - | 356 | 286 | 210 | 70 | 70 | 51 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .