| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Simone Iacoponi | 36 | 34 | 3 | 2 | 2 | 2 |
Dejan Kulusevski | 36 | 33 | 3 | 3 | 10 | 10 |
Luigi Sepe | 34 | 34 | - | - | - | - |
Bruno Alves | 33 | 31 | 2 | 2 | 4 | - |
Matteo Darmian | 33 | 30 | 3 | 3 | 3 | 1 |
Riccardo Gagliolo | 32 | 31 | 4 | 1 | 9 | 3 |
Hernani | 32 | 27 | 5 | 5 | 8 | - |
Gervinho | 31 | 27 | 5 | 4 | 14 | 7 |
Juraj Kucka | 26 | 22 | 5 | 4 | 5 | 6 |
Antonino Barilla | 26 | 20 | 14 | 6 | 11 | 1 |
Andreas Cornelius | 26 | 17 | 12 | 9 | 6 | 12 |
Gaston Brugman | 23 | 17 | 18 | 6 | 11 | - |
Giuseppe Pezzella | 22 | 8 | 28 | 14 | 2 | - |
Jasmin Kurtic | 20 | 18 | 2 | 2 | 3 | 2 |
Mattia Sprocati | 20 | 4 | 34 | 16 | 4 | 1 |
Roberto Inglese | 17 | 8 | 9 | 9 | 7 | 4 |
Matteo Scozzarella | 16 | 12 | 11 | 4 | 9 | - |
Kastriot Dermaku | 16 | 10 | 21 | 6 | 2 | - |
Alberto Grassi | 16 | 6 | 17 | 10 | 5 | 1 |
Vincent Laurini | 15 | 10 | 22 | 5 | 7 | - |
Yann Karamoh | 14 | 5 | 21 | 9 | 5 | 1 |
Gianluca Caprari | 12 | 7 | 10 | 5 | 6 | 2 |
Luca Siligardi | 12 | 3 | 16 | 9 | 3 | - |
Simone Colombi | 4 | 4 | 34 | - | - | - |
Vasco Regini | 2 | - | 16 | 2 | - | - |
Ionut Radu | - | - | 7 | - | - | - |
Edoardo Corvi | - | - | 4 | - | - | - |
Fabio Ceravolo | - | - | 1 | - | - | - |
Pepin | - | - | 1 | - | - | - |
Luca Rigoni | - | - | 1 | - | - | - |
Drissa Gui Camara | - | - | 6 | - | - | - |
Mark Kosznovszky | - | - | 3 | - | - | - |
Botond Balogh | - | - | 4 | - | - | - |
Andrea Adorante | - | - | 3 | - | - | - | 554 | 418 | 345 | 136 | 136 | 53 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .