| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Gianluigi Donnarumma | 36 | 36 | - | - | 2 | - |
Hakan Calhanoglu | 36 | 34 | 2 | 2 | 15 | 3 |
Ricardo Rodriguez | 35 | 35 | 1 | - | 5 | - |
Suso | 35 | 35 | 1 | - | 12 | 7 |
Franck Kessie | 34 | 34 | 1 | - | 3 | 7 |
Patrick Cutrone | 34 | 12 | 24 | 22 | 3 | 3 |
Alessio Romagnoli | 32 | 32 | - | - | 1 | 2 |
Tiemoue Bakayoko | 32 | 26 | 11 | 6 | 4 | 1 |
Samu Castillejo | 31 | 8 | 30 | 23 | 5 | 4 |
Mateo Musacchio | 29 | 29 | 5 | - | - | 1 |
Davide Calabria | 26 | 22 | 8 | 4 | 7 | 2 |
Fabio Borini | 20 | 10 | 24 | 10 | 4 | 2 |
Diego Laxalt | 20 | 6 | 32 | 14 | 3 | - |
Krzysztof Piatek | 18 | 16 | 2 | 2 | 8 | 8 |
Ignazio Abate | 18 | 15 | 23 | 3 | 7 | - |
Lucas Biglia | 16 | 13 | 12 | 3 | 3 | 1 |
Gonzalo Higuain | 15 | 15 | - | - | 2 | 6 |
Lucas Paqueta | 13 | 12 | 2 | 1 | 9 | 1 |
Cristian Zapata | 13 | 12 | 17 | 1 | 1 | - |
Andrea Conti | 12 | 4 | 23 | 8 | 3 | - |
Giacomo Bonaventura | 8 | 8 | - | - | 5 | 3 |
Jose Mauri | 5 | 2 | 30 | 3 | 2 | - |
Pepe Reina | 4 | 2 | 31 | 2 | - | - |
Andrea Bertolacci | - | - | 34 | - | - | - |
Emanuele Torrasi | - | - | 3 | - | - | - |
Frank Tsadjout | - | - | 9 | - | - | - |
Ivan Strinic | - | - | 7 | - | - | - |
Raoul Bellanova | - | - | 2 | - | - | - |
Stefan Simic | - | - | 14 | - | - | - |
Antonio Donnarumma | - | - | 37 | - | - | - |
Alen Halilovic | - | - | 13 | - | - | - |
Mattia Caldara | - | - | 12 | - | - | - |
Riccardo Montolivo | - | - | 16 | - | - | - |
Marco Brescianini | - | - | 2 | - | - | - |
Alessandro Plizzari | - | - | 7 | - | - | - | 522 | 418 | 435 | 104 | 104 | 51 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .