| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Antoine Griezmann | 37 | 37 | - | - | 6 | 15 |
Jan Oblak | 37 | 37 | - | - | - | - |
Angel Correa | 36 | 20 | 17 | 16 | 14 | 3 |
Rodri Hernandez | 34 | 32 | 5 | 2 | 9 | 3 |
Saul Niguez | 33 | 32 | 2 | 1 | - | 4 |
Thomas Partey | 32 | 22 | 14 | 10 | 5 | 3 |
Thomas Lemar | 31 | 22 | 10 | 9 | 17 | 2 |
Jorge Koke | 30 | 29 | 1 | 1 | 2 | 3 |
Diego Godin | 30 | 28 | 3 | 2 | 1 | 3 |
Filipe Luis | 27 | 24 | 5 | 3 | 9 | 2 |
Santiago Arias | 25 | 20 | 11 | 5 | 4 | 1 |
Juanfran | 22 | 18 | 14 | 4 | 3 | - |
Jose Maria Gimenez | 21 | 19 | 6 | 2 | 2 | - |
Vitolo | 20 | 5 | 25 | 15 | 4 | - |
Stefan Savic | 18 | 17 | 5 | 1 | 2 | - |
Nikola Kalinic | 17 | 7 | 24 | 10 | 7 | 2 |
Diego Costa | 16 | 14 | 2 | 2 | 5 | 2 |
Alvaro Morata | 15 | 13 | 3 | 2 | 8 | 6 |
Lucas Hernandez | 14 | 13 | 3 | 1 | 3 | 1 |
Francisco Montero | 9 | 4 | 17 | 5 | 2 | - |
Gelson Martins | 8 | 1 | 14 | 7 | 1 | - |
Victor Mollejo | 4 | - | 8 | 4 | - | - |
Antonio Moya | 1 | 1 | 8 | - | - | - |
Andres Solano | 1 | 1 | 2 | - | 1 | - |
Rafael Munoz | 1 | 1 | - | - | - | - |
Antonio Adan | 1 | 1 | 36 | - | - | - |
Sergio Camello | 1 | - | 3 | 1 | - | 1 |
Borja Garces | 1 | - | 10 | 1 | - | 1 |
Joaquin Munoz | 1 | - | 9 | 1 | - | - |
Cristian Rodriguez | - | - | 1 | - | - | - |
Alberto Rodriguez | - | - | 1 | - | - | - |
Alex Dos Santos | - | - | 2 | - | - | - |
Nehuen Perez | - | - | 2 | - | - | - |
Manu Sanchez | - | - | 1 | - | - | - |
Gustavo Assuncao | - | - | 1 | - | - | - |
Mikel Carro | - | - | 1 | - | - | - | 523 | 418 | 266 | 105 | 105 | 52 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .