| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Koen Casteels | 34 | 34 | - | - | - | - |
Paul Verhaegh | 31 | 30 | 2 | 1 | 5 | 2 |
Yunis Malli | 31 | 24 | 9 | 7 | 8 | 5 |
Divock Origi | 31 | 22 | 9 | 9 | 8 | 6 |
Daniel Didavi | 30 | 26 | 5 | 4 | 15 | 9 |
Maximilian Arnold | 29 | 28 | 2 | 1 | 1 | 2 |
Josuha Guilavogui | 29 | 27 | 3 | 2 | 5 | 3 |
Robin Knoche | 24 | 24 | 10 | - | 2 | 1 |
William | 22 | 19 | 7 | 3 | 5 | - |
Landry Dimata | 21 | 9 | 19 | 12 | 7 | - |
Ohis Felix Uduokhai | 19 | 17 | 5 | 2 | - | 1 |
Yannick Gerhardt | 17 | 12 | 10 | 5 | 1 | 1 |
Marcel Tisserand | 16 | 14 | 4 | 2 | 2 | - |
Renato Steffen | 16 | 6 | 11 | 10 | 3 | - |
Josip Brekalo | 13 | 10 | 6 | 3 | 9 | 3 |
Riechedly Bazoer | 13 | 6 | 17 | 7 | 4 | - |
Mario Gomez | 12 | 11 | 1 | 1 | 2 | 1 |
Victor Osimhen | 12 | 3 | 20 | 9 | 1 | - |
Ignacio Camacho | 11 | 11 | - | - | 2 | - |
Jeffrey Bruma | 11 | 11 | 4 | - | - | - |
John Anthony Brooks | 9 | 9 | 2 | - | 2 | - |
Jakub Blaszczykowski | 9 | 6 | 5 | 3 | 4 | 1 |
Luca Itter | 5 | 5 | 11 | - | 2 | - |
Admir Mehmedi | 5 | 3 | 3 | 2 | 1 | 1 |
Paul-Georges Ntep | 5 | 1 | 14 | 4 | 1 | - |
Elvis Rexhbecaj | 4 | 1 | 11 | 3 | - | - |
Paul Jaeckel | 3 | 3 | 3 | - | - | - |
Sebastian Jung | 2 | 1 | 6 | 1 | 1 | - |
Kaylen Hinds | 1 | 1 | 4 | - | - | - |
Dominik Franke | - | - | 1 | - | - | - |
Max Grun | - | - | 34 | - | - | - | 465 | 374 | 238 | 91 | 91 | 36 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .