| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Santi Cazorla | 38 | 38 | - | - | 11 | 9 |
Salomon Rondon | 37 | 29 | 8 | 8 | 15 | 11 |
Martin Demichelis | 35 | 33 | 2 | 2 | - | 3 |
Isco | 32 | 29 | 5 | 3 | 8 | 5 |
Sebastian Fernandez | 32 | 15 | 21 | 17 | 11 | 5 |
Nacho Monreal | 31 | 28 | 7 | 3 | 2 | - |
Joris Mathijsen | 28 | 28 | 6 | - | 1 | - |
Willy Caballero | 28 | 28 | - | - | 1 | - |
Ruud van Nistelrooy | 28 | 10 | 25 | 18 | 6 | 4 |
Jeremy Toulalan | 25 | 25 | - | - | 2 | 3 |
Jesus Gamez | 25 | 24 | 9 | 1 | 1 | - |
Eliseu | 25 | 19 | 11 | 6 | 9 | 2 |
Duda | 25 | 14 | 18 | 11 | 11 | 1 |
Joaquin | 23 | 19 | 6 | 4 | 13 | 2 |
Weligton | 19 | 19 | 5 | - | - | 1 |
Sergio Sanchez | 19 | 16 | 17 | 3 | 2 | - |
Enzo Maresca | 19 | 9 | 19 | 10 | 7 | 2 |
Ignacio Camacho | 13 | 8 | 16 | 5 | - | 1 |
Diego Buonanotte | 10 | 4 | 22 | 6 | 4 | - |
Carlos Kameni | 9 | 8 | 11 | 1 | - | - |
Recio | 8 | 4 | 8 | 4 | 4 | - |
Juanmi | 6 | 2 | 10 | 4 | 2 | 1 |
Apono | 6 | 2 | 5 | 4 | 1 | 1 |
Julio Baptista | 4 | 4 | - | - | 2 | 1 |
Ruben | 4 | 2 | 21 | 2 | - | - |
Francisco Portillo | 2 | 1 | 5 | 1 | - | - |
Kris Stadsgaard | - | - | 1 | - | - | - |
Pol | - | - | 2 | - | - | - |
Toni | - | - | 1 | - | - | - | 531 | 418 | 261 | 113 | 113 | 52 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .