| MD | Players | Clubs | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 15-Sep-2021 |  Artur Boruc | Legia Warsaw | Poland | 20-Feb-1980 | 41(208) |
| 17-Mar-2022 |  Joaquin | Real Betis | Spain | 21-Jul-1981 | 40(239) |
| 18-May-2022 |  Allan McGregor | Rangers | Scotland | 31-Jan-1982 | 40(107) |
| 17-Mar-2022 |  Pepe | FC Porto | Portugal | 26-Feb-1983 | 39(20) |
| 09-Mar-2022 | Claudio Bravo | Real Betis | Chile | 13-Apr-1983 | 38(331) |
| 14-Apr-2022 |  Makoto Hasebe | Eintracht Frankfurt | Japan | 18-Jan-1984 | 38(87) |
| 21-Oct-2021 |  Thomas Mikkelsen | Brondby | Denmark | 27-Aug-1983 | 38(56) |
| 24-Feb-2022 | Mathieu Valbuena | Olympiakos | France | 28-Sep-1984 | 37(149) |
| 18-May-2022 | Steven Davis | Rangers | Northern Ireland | 01-Jan-1985 | 37(137) |
| 17-Mar-2022 | Bafetimbi Gomis | Galatasaray SK | France | 06-Aug-1985 | 36(223) |
| 16-Sep-2021 |  Lukasz Fabianski | West Ham United | Poland | 18-Apr-1985 | 36(151) |
| 04-Nov-2021 | Jose Sosa | Fenerbahce | Argentina | 19-Jun-1985 | 36(138) |
| 17-Mar-2022 |  Jesus Navas | Sevilla | Spain | 21-Nov-1985 | 36(116) |
| 24-Feb-2022 |  David Silva | Real Sociedad | Spain | 08-Jan-1986 | 36(47) |
| 04-Nov-2021 | Guilherme | Lokomotiv Moscow | Brazil | 12-Dec-1985 | 35(328) |
| 25-Nov-2021 | Fernando Muslera | Galatasaray SK | Uruguay | 16-Jun-1986 | 35(163) |
| 24-Feb-2022 | Andres Guardado | Real Betis | Mexico | 28-Sep-1986 | 35(150) |
| 24-Feb-2022 |  Stefan Radu | SS Lazio | Romania | 22-Oct-1986 | 35(126) |
| 17-Mar-2022 | Ryan Babel | Galatasaray SK | Netherlands | 19-Dec-1986 | 35(89) |
| 07-Apr-2022 |  Gerard Pique | Barcelona | Spain | 02-Feb-1987 | 35(65) |
| 24-Feb-2022 | Lucas Leiva | SS Lazio | Brazil | 09-Jan-1987 | 35(47) |
| 09-Dec-2021 |  Kasper Schmeichel | Leicester City | Denmark | 05-Nov-1986 | 35(35) |
| 24-Feb-2022 | Youssef El-Arabi | Olympiakos | Morocco | 03-Feb-1987 | 35(22) |
| 17-Feb-2022 | Mihail Kerzhakov | Zenit St Petersburg | Russia | 28-Jan-1987 | 35(21) |
| 14-Apr-2022 | Mark Noble | West Ham United | England | 08-May-1987 | 34(342) |
| 09-Dec-2021 | Jamie Vardy | Leicester City | England | 11-Jan-1987 | 34(333) |
| 24-Feb-2022 |  Dries Mertens | Napoli | Belgium | 06-May-1987 | 34(295) |
| 25-Nov-2021 |  Joe Hart | Celtic | England | 19-Apr-1987 | 34(221) |
| 04-Nov-2021 |  Dimitri Payet | Olympique Marseille | France | 29-Mar-1987 | 34(221) |
| 24-Feb-2022 | Fernando | Sevilla | Brazil | 25-Jul-1987 | 34(215) |
| 24-Feb-2022 | Pedro Rodriguez | SS Lazio | Spain | 28-Jul-1987 | 34(212) |
| 17-Mar-2022 | Milan Borjan | Red Star Belgrade | Canada | 23-Oct-1987 | 34(146) |
| 16-Sep-2021 |  Francesc Fabregas | AS Monaco | Spain | 04-May-1987 | 34(136) |
| 04-Nov-2021 | Florin Nita | Sparta Prague | Romania | 03-Jul-1987 | 34(125) |
| 04-Nov-2021 |  Eran Zahavi | PSV Eindhoven | Israel | 25-Jul-1987 | 34(103) |
| 09-Dec-2021 | Jon McLaughlin | Rangers | Scotland | 09-Sep-1987 | 34(92) |
| 21-Oct-2021 | Luiz Gustavo | Fenerbahce | Brazil | 23-Jul-1987 | 34(91) |
| 04-Nov-2021 | Adam Bogdan | Ferencvaros | Hungary | 27-Sep-1987 | 34(39) |
| 25-Nov-2021 | Artur Jedrzejczyk | Legia Warsaw | Poland | 04-Nov-1987 | 34(22) |
| 14-Apr-2022 | Andre Castro | Sporting Braga | Portugal | 02-Apr-1988 | 34(12) |
| 24-Feb-2022 | Papu Gomez | Sevilla | Argentina | 15-Feb-1988 | 34(10) |
| 17-Mar-2022 | Ivan Rakitic | Sevilla | Croatia | 10-Mar-1988 | 34(7) |
MD = Match date,
DOB = Date Of Birth,
A(D) = Age(Days).