| MD | Players | Clubs | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 02-Nov-2018 |  Nick Rimando | Real Salt Lake | United States | 17-Jun-1979 | 39(139) |
| 02-Nov-2018 | Kyle Beckerman | Real Salt Lake | United States | 23-Apr-1982 | 36(193) |
| 02-Nov-2018 | Jordan Harvey | Los Angeles FC | United States | 28-Jan-1984 | 34(279) |
| 02-Nov-2018 | Federico Higuain | Columbus Crew | Argentina | 25-Oct-1984 | 34(8) |
| 02-Nov-2018 | Benny Feilhaber | Los Angeles FC | United States | 19-Jan-1985 | 33(287) |
| 02-Nov-2018 | Frederic Brillant | DC United | France | 26-Jun-1985 | 33(129) |
| 02-Nov-2018 | Wayne Rooney | DC United | England | 24-Oct-1985 | 33(9) |
| 02-Nov-2018 | Harrison Afful | Columbus Crew | Ghana | 24-Jun-1986 | 32(131) |
| 02-Nov-2018 | Lee Nguyen | Los Angeles FC | United States | 07-Oct-1986 | 32(26) |
| 02-Nov-2018 | Nedum Onuoha | Real Salt Lake | England | 12-Nov-1986 | 31(355) |
| 02-Nov-2018 | Danilo Silva | Los Angeles FC | Brazil | 24-Nov-1986 | 31(344) |
| 02-Nov-2018 | Steven Beltashour | Los Angeles FC | Iran | 01-Feb-1987 | 31(275) |
| 02-Nov-2018 | Pedro Santos | Columbus Crew | Portugal | 22-Apr-1988 | 30(194) |
| 02-Nov-2018 | Luke Mulholland | Real Salt Lake | England | 07-Aug-1988 | 30(87) |
| 02-Nov-2018 | Justin Meram | Columbus Crew | Iraq | 04-Dec-1988 | 29(333) |
| 02-Nov-2018 | Carlos Vela | Los Angeles FC | Mexico | 01-Mar-1989 | 29(246) |
| 02-Nov-2018 | Marcelo Silva | Real Salt Lake | Uruguay | 21-Mar-1989 | 29(226) |
| 02-Nov-2018 | Damir Kreilach | Real Salt Lake | Croatia | 16-Apr-1989 | 29(200) |
| 02-Nov-2018 | Adama Diomande | Los Angeles FC | Norway | 14-Feb-1990 | 28(261) |
| 02-Nov-2018 | Gaston Sauro | Columbus Crew | Argentina | 23-Feb-1990 | 28(252) |
| 02-Nov-2018 | Jonathan Mensah | Columbus Crew | Ghana | 13-Jul-1990 | 28(112) |
| 02-Nov-2018 | Bill Hamid | DC United | United States | 25-Nov-1990 | 27(342) |
| 02-Nov-2018 | Steve Birnbaum | DC United | United States | 23-Jan-1991 | 27(283) |
| 02-Nov-2018 | Gyasi Zardes | Columbus Crew | United States | 02-Sep-1991 | 27(61) |
| 02-Nov-2018 | Will Trapp | Columbus Crew | United States | 15-Jan-1993 | 25(291) |
| 02-Nov-2018 | Tyler Miller | Los Angeles FC | United States | 12-Mar-1993 | 25(235) |
| 02-Nov-2018 | Joseph Mora | DC United | Costa Rica | 15-Mar-1993 | 25(232) |
| 02-Nov-2018 | Walker Zimmerman | Los Angeles FC | United States | 19-May-1993 | 25(167) |
| 02-Nov-2018 | Ulises Segura | DC United | Costa Rica | 23-Jun-1993 | 25(132) |
| 02-Nov-2018 | Junior Moreno | DC United | Venezuela | 20-Jul-1993 | 25(105) |
| 02-Nov-2018 | Luciano Acosta | DC United | Argentina | 31-May-1994 | 24(155) |
| 02-Nov-2018 | Albert Rusnak | Real Salt Lake | Slovakia | 07-Jul-1994 | 24(118) |
| 02-Nov-2018 | Yamil Asad | DC United | Argentina | 27-Jul-1994 | 24(98) |
| 02-Nov-2018 | Paul Arriola | DC United | United States | 05-Feb-1995 | 23(270) |
| 02-Nov-2018 | Zack Steffen | Columbus Crew | United States | 02-Apr-1995 | 23(214) |
| 02-Nov-2018 | Russell Canouse | DC United | United States | 11-Jun-1995 | 23(144) |
| 02-Nov-2018 | Corey Baird | Real Salt Lake | United States | 30-Jan-1996 | 22(277) |
| 02-Nov-2018 | Artur | Columbus Crew | Brazil | 11-Mar-1996 | 22(236) |
| 02-Nov-2018 | Jefferson Savarino | Real Salt Lake | Venezuela | 11-Nov-1996 | 21(356) |
| 02-Nov-2018 | Latif Blessing | Los Angeles FC | Ghana | 30-Dec-1996 | 21(307) |
| 02-Nov-2018 | Aaron Herrera | Real Salt Lake | United States | 06-Jun-1997 | 21(149) |
| 02-Nov-2018 | Brooks Lennon | Real Salt Lake | United States | 22-Sep-1997 | 21(41) |
| 02-Nov-2018 | Diego Rossi | Los Angeles FC | Uruguay | 05-Mar-1998 | 20(242) |
| 02-Nov-2018 | Milton Valenzuela | Columbus Crew | Argentina | 13-Aug-1998 | 20(81) |
MD = Match date,
DOB = Date Of Birth,
A(D) = Age(Days).