| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 12-Sep-2021 | lose |  Atletico Madrid | 1-2 | home |
| 19-Sep-2021 | draw |  Real Betis | 2-2 | away |
| 22-Sep-2021 | win |  CD Alaves | 1-0 | home |
| 03-Oct-2021 | win |  Real Madrid | 2-1 | home |
| 18-Oct-2021 | win |  Cadiz CF | 2-0 | home |
| 26-Oct-2021 | draw |  Athletic Bilbao | 1-1 | home |
| 06-Nov-2021 | win |  Granada CF | 2-0 | home |
| 28-Nov-2021 | win |  Real Sociedad | 1-0 | home |
| 11-Dec-2021 | win |  Levante | 4-3 | home |
| 18-Jan-2022 | draw | Cadiz CF | 2-2 | away |
| 21-Jan-2022 | lose | Real Betis | 1-4 | home |
| 07-Feb-2022 | lose | Athletic Bilbao | 2-1 | away |
| 05-Mar-2022 | win |  Getafe | 2-0 | home |
| 12-Mar-2022 | draw | Levante | 1-1 | away |
| 20-Mar-2022 | win |  RCD Mallorca | 1-0 | home |
| 10-Apr-2022 | win |  Celta Vigo | 1-0 | home |
Overall ( 9 wins,4 draw,3 lost )
Home ( 9 wins,1 draw,2 lost )
Away ( 0 wins,3 draw,1 lost )
OPP = Opposition,
FS = Final score.