| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 21-Aug-2021 | draw |  Barcelona | 1-1 | home |
| 28-Aug-2021 | win |  Celta Vigo | 0-1 | away |
| 11-Sep-2021 | win |  RCD Mallorca | 2-0 | home |
| 25-Sep-2021 | draw |  Valencia | 1-1 | away |
| 01-Oct-2021 | win |  CD Alaves | 1-0 | home |
| 23-Oct-2021 | win |  Villarreal | 2-1 | home |
| 26-Nov-2021 | draw |  Granada CF | 2-2 | home |
| 19-Dec-2021 | win |  Real Betis | 3-2 | home |
| 23-Jan-2022 | win |  Rayo Vallecano | 0-1 | away |
| 20-Feb-2022 | win |  Real Sociedad | 4-0 | home |
| 07-Mar-2022 | win |  Levante | 3-1 | home |
| 03-Apr-2022 | win |  Elche CF | 2-1 | home |
| 09-Apr-2022 | draw | Villarreal | 1-1 | away |
| 21-Apr-2022 | win |  Cadiz CF | 2-3 | away |
| 30-Apr-2022 | win |  Atletico Madrid | 2-0 | home |
| 15-May-2022 | win |  Osasuna | 2-0 | home |
Overall ( 12 wins,4 draw,0 lost )
Home ( 9 wins,2 draw,0 lost )
Away ( 3 wins,2 draw,0 lost )
OPP = Opposition,
FS = Final score.