| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 29-Aug-2021 | win |  Cadiz CF | 2-3 | away |
| 23-Sep-2021 | lose |  Real Betis | 1-3 | home |
| 30-Oct-2021 | lose |  Sevilla | 2-0 | away |
| 07-Nov-2021 | lose |  Real Sociedad | 0-2 | home |
| 20-Nov-2021 | lose |  Atletico Madrid | 1-0 | away |
| 12-Dec-2021 | draw |  Barcelona | 2-2 | home |
| 19-Dec-2021 | lose |  Getafe | 1-0 | away |
| 19-Jan-2022 | lose |  Celta Vigo | 2-0 | away |
| 19-Feb-2022 | lose | Atletico Madrid | 0-3 | home |
| 27-Feb-2022 | lose | Real Sociedad | 1-0 | away |
| 13-Mar-2022 | lose | Barcelona | 4-0 | away |
| 03-Apr-2022 | lose | Real Betis | 4-1 | away |
| 20-Apr-2022 | lose |  Real Madrid | 1-3 | home |
| 15-May-2022 | lose |  Athletic Bilbao | 2-0 | away |
| 22-May-2022 | lose |  RCD Mallorca | 0-2 | home |
Overall ( 1 wins,1 draw,13 lost )
Home ( 0 wins,1 draw,5 lost )
Away ( 1 wins,0 draw,8 lost )
OPP = Opposition,
FS = Final score.