| A(D) | Clubs | VS | MD | |
|---|---|---|---|---|
| 23(202) | Shakhtar Donetsk | KRC Genk | 03-Aug-2021 | Match Details |
| 24(201) | Celtic | FC Midtylland | 28-Jul-2021 | Match Details |
| 24(155) | FC Midtylland | PSV Eindhoven | 10-Aug-2021 | Match Details |
| 25(197) | KRC Genk | Shakhtar Donetsk | 03-Aug-2021 | Match Details |
| 25(285) | Rapid Wien | Sparta Prague | 28-Jul-2021 | Match Details |
| 25(286) | Spartak Moscow | Benfica | 10-Aug-2021 | Match Details |
| 25(51) | AS Monaco | Sparta Prague | 03-Aug-2021 | Match Details |
| 25(76) | BSC Young Boys | CFR Cluj | 03-Aug-2021 | Match Details |
| 26(284) | Slavia Prague | Ferencvaros | 04-Aug-2021 | Match Details |
| 26(340) | FC Sheriff Tiraspol | Alashkert FC | 28-Jul-2021 | Match Details |
| 26(13) | PSV Eindhoven | FC Midtylland | 10-Aug-2021 | Match Details |
| 26(15) | Olympiakos | Neftchi Baku | 28-Jul-2021 | Match Details |
| 26(44) | Mura 05 | KF Shkendija | 06-Jul-2021 | Match Details |
| 26(67) | Dinamo Zagreb | Legia Warsaw | 04-Aug-2021 | Match Details |
| 26(74) | Kairat | Red Star Belgrade | 28-Jul-2021 | Match Details |
| 27(191) | Sparta Prague | AS Monaco | 03-Aug-2021 | Match Details |
| 27(200) | Ferencvaros | Slavia Prague | 04-Aug-2021 | Match Details |
| 27(301) | Ludogorets Razgrad | Mura 05 | 21-Jul-2021 | Match Details |
| 27(312) | Flora Talinn | Legia Warsaw | 27-Jul-2021 | Match Details |
| 27(18) | Galatasaray SK | PSV Eindhoven | 28-Jul-2021 | Match Details |
| 27(36) | Benfica | PSV Eindhoven | 18-Aug-2021 | Match Details |
| 28(193) | FK Zalgiris Vilnius | Ferencvaros | 27-Jul-2021 | Match Details |
| 28(253) | HJK Helsinki | Malmo FF | 27-Jul-2021 | Match Details |
| 28(318) | Neftchi Baku | Olympiakos | 28-Jul-2021 | Match Details |
| 28(38) | Legia Warsaw | Dinamo Zagreb | 04-Aug-2021 | Match Details |
| 28(97) | KF Shkendija | Mura 05 | 13-Jul-2021 | Match Details |
| 29(14) | Malmo FF | Ludogorets Razgrad | 24-Aug-2021 | Match Details |
| 29(183) | Omonia Nicosia | Dinamo Zagreb | 27-Jul-2021 | Match Details |
| 30(206) | Rangers | Malmo FF | 03-Aug-2021 | Match Details |
| 30(233) | Slovan Bratislava | BSC Young Boys | 28-Jul-2021 | Match Details |
| 30(261) | Alashkert FC | FC Sheriff Tiraspol | 28-Jul-2021 | Match Details |
| 30(335) | Red Star Belgrade | Kairat | 28-Jul-2021 | Match Details |
| 31(252) | Lincoln Red Imps | CFR Cluj | 28-Jul-2021 | Match Details |
| 31(304) | CFR Cluj | BSC Young Boys | 03-Aug-2021 | Match Details |
MD = Match date,
A(D) = Age(Days).