| A(D) | Clubs | VS | MD | |
|---|---|---|---|---|
| 32(240) | CFR Cluj | AZ Alkmaar | 04-Nov-2021 | Match Details |
| 31(52) | Lincoln Red Imps | Slovan Bratislava | 04-Nov-2021 | Match Details |
| 31(303) | Alashkert FC | HJK Helsinki | 25-Nov-2021 | Match Details |
| 30(136) | Anorthosis Famagusta | Partizan Belgrade | 16-Sep-2021 | Match Details |
| 30(112) | PAOK Salonika | Slovan Bratislava | 25-Nov-2021 | Match Details |
| 30(264) | FK Jablonec | Randers FC | 04-Nov-2021 | Match Details |
| 29(159) | Omonia Nicosia | Kairat | 16-Sep-2021 | Match Details |
| 29(66) | Kairat | FC Basel | 25-Nov-2021 | Match Details |
| 29(41) | Slovan Bratislava | Lincoln Red Imps | 04-Nov-2021 | Match Details |
| 29(2) | KAA Gent | Partizan Belgrade | 04-Nov-2021 | Match Details |
| 29(282) | Partizan Belgrade | Sparta Prague | 17-Feb-2022 | Match Details |
| 28(153) | Leicester City | AS Roma | 28-Apr-2022 | Match Details |
| 28(145) | 1. FC Union Berlin | Feyenoord | 04-Nov-2021 | Match Details |
| 28(138) | Maccabi Tel Aviv | HJK Helsinki | 04-Nov-2021 | Match Details |
| 28(123) | Maccabi Haifa | Slavia Prague | 04-Nov-2021 | Match Details |
| 28(92) | HJK Helsinki | Alashkert FC | 25-Nov-2021 | Match Details |
| 28(78) | Fenerbahce | Slavia Prague | 24-Feb-2022 | Match Details |
| 28(1) | Qarabag FK | Olympique Marseille | 24-Feb-2022 | Match Details |
| 28(247) | Randers FC | AZ Alkmaar | 16-Sep-2021 | Match Details |
| 28(240) | Flora Talinn | Anorthosis Famagusta | 04-Nov-2021 | Match Details |
| 28(225) | LASK Linz | Maccabi Tel Aviv | 30-Sep-2021 | Match Details |
| 27(185) | CSKA Sofia | FC Zorya Luhansk | 04-Nov-2021 | Match Details |
| 27(138) | AS Roma | FC Zorya Luhansk | 25-Nov-2021 | Match Details |
| 27(93) | Olympique Marseille | PAOK Salonika | 14-Apr-2022 | Match Details |
| 27(66) | Slavia Prague | Feyenoord | 07-Apr-2022 | Match Details |
| 27(21) | FC Zorya Luhansk | CSKA Sofia | 21-Oct-2021 | Match Details |
| 27(358) | Tottenham Hotspur | Vitesse Arnhem | 04-Nov-2021 | Match Details |
| 27(276) | PSV Eindhoven | Leicester City | 14-Apr-2022 | Match Details |
| 27(254) | Celtic | Bodo/Glimt | 24-Feb-2022 | Match Details |
| 27(249) | Mura 05 | Stade Rennes | 04-Nov-2021 | Match Details |
| 27(233) | FC Copenhagen | PSV Eindhoven | 17-Mar-2022 | Match Details |
| 27(231) | Bodo/Glimt | AS Roma | 07-Apr-2022 | Match Details |
| 27(198) | Stade Rennes | Vitesse Arnhem | 25-Nov-2021 | Match Details |
| 26(39) | Feyenoord | Slavia Prague | 25-Nov-2021 | Match Details |
| 26(33) | FC Basel | Kairat | 25-Nov-2021 | Match Details |
| 25(84) | AZ Alkmaar | Randers FC | 16-Sep-2021 | Match Details |
| 25(37) | Vitesse Arnhem | AS Roma | 10-Mar-2022 | Match Details |
| 25(305) | FC Midtylland | PAOK Salonika | 17-Feb-2022 | Match Details |
| 24(120) | Sparta Prague | Partizan Belgrade | 17-Feb-2022 | Match Details |
| 24(5) | Rapid Wien | Vitesse Arnhem | 24-Feb-2022 | Match Details |
MD = Match date,
A(D) = Age(Days).