| 5 | Robson Ponte | Group Stage | UEFA Champions League 04/05 |
| 4 | Robert Andrich | Group Stage | UEFA Champions League 22/23 |
| 4 | Emre Can | Group Stage | UEFA Champions League 13/14 |
| 4 | Yildiray Basturk | First Group Stage | UEFA Champions League 02/03 |
| 4 | Jens Nowotny | First Group Stage | UEFA Champions League 01/02 |
| 4 | Boris Zivkovic | First Group Stage | UEFA Champions League 01/02 |
| 4 | Diego Placente | First Group Stage | UEFA Champions League 01/02 |
| 3 | Mitchel Bakker | Group Stage | UEFA Champions League 22/23 |
| 3 | Piero Hincapie | Group Stage | UEFA Champions League 22/23 |
| 3 | Benjamin Henrichs | Group Stage | UEFA Champions League 16/17 |
| 3 | Kevin Kampl | Group Stage | UEFA Champions League 15/16 |
| 3 | Kyriakos Papadopoulos | Group Stage | UEFA Champions League 15/16 |
| 3 | Wendell | Group Stage | UEFA Champions League 14/15 |
| 3 | Emir Spahic | Group Stage | UEFA Champions League 14/15 |
| 3 | Gonzalo Castro | Group Stage | UEFA Champions League 11/12 |
| 3 | Emerson | Quarter-finals | UEFA Champions League 97/98 |
| 3 | Markus Happe | Quarter-finals | UEFA Champions League 97/98 |
| 3 | Paul Freier | Group Stage | UEFA Champions League 04/05 |
| 3 | Diego Placente | Group Stage | UEFA Champions League 04/05 |
| 3 | Thomas Kleine | First Group Stage | UEFA Champions League 02/03 |
| 3 | Hanno Balitsch | First Group Stage | UEFA Champions League 02/03 |
| 3 | Ulf Kirsten | First Group Stage | UEFA Champions League 99/00 |
| 3 | Carsten Ramelow | First Group Stage | UEFA Champions League 01/02 |
| 3 | Ze Roberto | Quarter-finals | UEFA Champions League 01/02 |
| 3 | Lucio | First Group Stage | UEFA Champions League 01/02 |
| 3 | Jens Nowotny | First Group Stage | UEFA Champions League 00/01 |
| 2 | Exequiel Palacios | Group Stage | UEFA Champions League 22/23 |
| 2 | Charles Aranguiz | Group Stage | UEFA Champions League 19/20 |
| 2 | Karim Bellarabi | Group Stage | UEFA Champions League 19/20 |
| 2 | Wendell | Group Stage | UEFA Champions League 16/17 |
| 2 | Aleksander Dragovic | Group Stage | UEFA Champions League 16/17 |
| 2 | Wendell | Group Stage | UEFA Champions League 15/16 |
| 2 | Sebastian Boenisch | Group Stage | UEFA Champions League 14/15 |
| 2 | Kyriakos Papadopoulos | Round of 16 | UEFA Champions League 14/15 |
| 2 | Stefan Kiessling | Round of 16 | UEFA Champions League 14/15 |
| 2 | Omer Toprak | Group Stage | UEFA Champions League 14/15 |
| 2 | Lars Bender | Group Stage | UEFA Champions League 13/14 |
| 2 | Gonzalo Castro | Group Stage | UEFA Champions League 13/14 |
| 2 | Omer Toprak | Group Stage | UEFA Champions League 11/12 |
| 2 | Michael Ballack | Group Stage | UEFA Champions League 11/12 |
| 2 | Eren Derdiyok | Group Stage | UEFA Champions League 11/12 |
| 2 | Simon Rolfes | Group Stage | UEFA Champions League 11/12 |
| 2 | Stefan Kiessling | Group Stage | UEFA Champions League 11/12 |
| 2 | Michal Kadlec | Group Stage | UEFA Champions League 11/12 |
| 2 | Stefan Beinlich | Group Stage | UEFA Champions League 97/98 |
| 2 | Carsten Ramelow | Quarter-finals | UEFA Champions League 97/98 |
| 2 | Ulf Kirsten | Quarter-finals | UEFA Champions League 97/98 |
| 2 | Hanno Balitsch | Group Stage | UEFA Champions League 04/05 |
| 2 | Bernd Schneider | Group Stage | UEFA Champions League 04/05 |
| 2 | Carsten Ramelow | Group Stage | UEFA Champions League 04/05 |
| 2 | Cris | Second Group Stage | UEFA Champions League 02/03 |
| 2 | Diego Placente | Second Group Stage | UEFA Champions League 02/03 |
| 2 | Bernd Schneider | First Group Stage | UEFA Champions League 99/00 |
| 2 | Thomas Brdaric | Second Group Stage | UEFA Champions League 01/02 |
| 2 | Zoltan Sebescen | First Group Stage | UEFA Champions League 01/02 |
| 2 | Michael Ballack | Second Group Stage | UEFA Champions League 01/02 |
| 1 | Odilon Kossounou | Group Stage | UEFA Champions League 22/23 |
| 1 | Paulinho | Group Stage | UEFA Champions League 22/23 |
| 1 | Jonathan Tah | Group Stage | UEFA Champions League 22/23 |
| 1 | Lukas Hradecky | Group Stage | UEFA Champions League 22/23 |
