| 5 | Jefferson Farfan | Group Stage | UEFA Champions League 10/11 |
| 5 | Jermaine Jones | Group Stage | UEFA Champions League 07/08 |
| 3 | Jermaine Jones | Group Stage | UEFA Champions League 13/14 |
| 3 | Marco Hoger | Group Stage | UEFA Champions League 12/13 |
| 3 | Jermaine Jones | Group Stage | UEFA Champions League 12/13 |
| 3 | Rafinha | Group Stage | UEFA Champions League 07/08 |
| 3 | Levan Kobiashvili | Group Stage | UEFA Champions League 05/06 |
| 3 | Rafinha | Group Stage | UEFA Champions League 05/06 |
| 3 | Gerald Asamoah | First Group Stage | UEFA Champions League 01/02 |
| 2 | Breel Embolo | Group Stage | UEFA Champions League 18/19 |
| 2 | Sebastian Rudy | Group Stage | UEFA Champions League 18/19 |
| 2 | Mark Uth | Group Stage | UEFA Champions League 18/19 |
| 2 | Benjamin Stambouli | Group Stage | UEFA Champions League 18/19 |
| 2 | Omar Mascarell | Group Stage | UEFA Champions League 18/19 |
| 2 | Kevin-Prince Boateng | Group Stage | UEFA Champions League 14/15 |
| 2 | Marco Hoger | Group Stage | UEFA Champions League 14/15 |
| 2 | Roman Neustadter | Round of 16 | UEFA Champions League 14/15 |
| 2 | Klass - Jan Huntelaar | Group Stage | UEFA Champions League 14/15 |
| 2 | Benedikt Howedes | Group Stage | UEFA Champions League 13/14 |
| 2 | Marco Hoger | Group Stage | UEFA Champions League 13/14 |
| 2 | Roman Neustadter | Group Stage | UEFA Champions League 13/14 |
| 2 | Joel Matip | Group Stage | UEFA Champions League 12/13 |
| 2 | Sead Kolasinac | Round of 16 | UEFA Champions League 12/13 |
| 2 | Ivan Rakitic | Group Stage | UEFA Champions League 10/11 |
| 2 | Lukas Schmitz | Round of 16 | UEFA Champions League 10/11 |
| 2 | Sergio Escudero | Round of 16 | UEFA Champions League 10/11 |
| 2 | Jose Manuel Jurado | Group Stage | UEFA Champions League 10/11 |
| 2 | Hans Sarpei | Quarter-finals | UEFA Champions League 10/11 |
| 2 | Klass - Jan Huntelaar | Group Stage | UEFA Champions League 10/11 |
| 2 | Kyriakos Papadopoulos | Quarter-finals | UEFA Champions League 10/11 |
| 2 | Raul | Quarter-finals | UEFA Champions League 10/11 |
| 2 | Heiko Westermann | Round of 16 | UEFA Champions League 07/08 |
| 2 | Marcelo Bordon | Group Stage | UEFA Champions League 07/08 |
| 2 | Kevin Kuranyi | Group Stage | UEFA Champions League 07/08 |
| 2 | Carlos Grossmuller | Group Stage | UEFA Champions League 07/08 |
| 2 | Fabian Ernst | Round of 16 | UEFA Champions League 07/08 |
| 2 | Dario Rodriguez | Group Stage | UEFA Champions League 05/06 |
| 2 | Victor Agali | First Group Stage | UEFA Champions League 01/02 |
| 1 | Salif Sane | Round of 16 | UEFA Champions League 18/19 |
| 1 | Guido Burgstaller | Round of 16 | UEFA Champions League 18/19 |
| 1 | Suat Serdar | Group Stage | UEFA Champions League 18/19 |
| 1 | Jeffrey Bruma | Round of 16 | UEFA Champions League 18/19 |
| 1 | Weston McKennie | Group Stage | UEFA Champions League 18/19 |
| 1 | Benjamin Goller | Group Stage | UEFA Champions League 18/19 |
| 1 | Dennis Aogo | Group Stage | UEFA Champions League 14/15 |
| 1 | Christian Fuchs | Group Stage | UEFA Champions League 14/15 |
| 1 | Jan Kirchhoff | Round of 16 | UEFA Champions League 14/15 |
| 1 | Kyriakos Papadopoulos | Round of 16 | UEFA Champions League 13/14 |
| 1 | Joel Matip | Group Stage | UEFA Champions League 13/14 |
| 1 | Dennis Aogo | Group Stage | UEFA Champions League 13/14 |
| 1 | Atsuto Uchida | Group Stage | UEFA Champions League 13/14 |
| 1 | Sead Kolasinac | Group Stage | UEFA Champions League 13/14 |
| 1 | Jefferson Farfan | Group Stage | UEFA Champions League 13/14 |
| 1 | Julian Draxler | Group Stage | UEFA Champions League 13/14 |
| 1 | Klass - Jan Huntelaar | Round of 16 | UEFA Champions League 13/14 |
| 1 | Christian Fuchs | Group Stage | UEFA Champions League 13/14 |
| 1 | Benedikt Howedes | Group Stage | UEFA Champions League 12/13 |
| 1 | Lewis Holtby | Group Stage | UEFA Champions League 12/13 |
| 1 | Christian Fuchs | Group Stage | UEFA Champions League 12/13 |
| 1 | Klass - Jan Huntelaar | Group Stage | UEFA Champions League 12/13 |
