| Goals | VS Club | Date | |
|---|---|---|---|
| 6 | Barcelona | 21-03-2021 | Match details |
| 5 | Sevilla | 10-03-2019 | Match details |
| 5 | Real Madrid | 10-02-2018 | Match details |
| 5 | Deportivo La Coruna | 05-12-2016 | Match details |
| 5 | Sporting Gijon | 22-01-2016 | Match details |
| 5 | Villarreal | 13-01-2014 | Match details |
| 5 | Real Madrid | 09-11-2013 | Match details |
| 5 | Barcelona | 19-08-2012 | Match details |
| 5 | Real Madrid | 24-03-2012 | Match details |
| 5 | Barcelona | 12-12-2010 | Match details |
| 4 | Barcelona | 21-08-2022 | Match details |
| 4 | Real Madrid | 05-03-2022 | Match details |
| 4 | Athletic Bilbao | 20-02-2022 | Match details |
| 4 | Real Betis | 12-12-2021 | Match details |
| 4 | Barcelona | 15-08-2021 | Match details |
| 4 | Villarreal | 27-01-2018 | Match details |
| 4 | Barcelona | 14-01-2018 | Match details |
| 4 | Real Betis | 01-10-2017 | Match details |
| 4 | Sevilla | 07-01-2017 | Match details |
| 4 | Barcelona | 28-11-2015 | Match details |
| 4 | Real Madrid | 31-01-2015 | Match details |
| 4 | Villarreal | 07-12-2014 | Match details |
| 4 | Real Madrid | 05-04-2014 | Match details |
| 4 | UD Almeria | 24-03-2014 | Match details |
| 4 | Atletico Madrid | 02-02-2014 | Match details |
La Liga 24/25 Top goal scorers