| 6 | Artyom Dzyuba | Group Stage | UEFA Champions League 15/16 |
| 5 | Roman Shirokov | Group Stage | UEFA Champions League 11/12 |
| 4 | Hulk | Group Stage | UEFA Champions League 15/16 |
| 4 | Hulk | Group Stage | UEFA Champions League 13/14 |
| 2 | Claudinho | Group Stage | UEFA Champions League 21/22 |
| 2 | Sardar Azmoun | Group Stage | UEFA Champions League 21/22 |
| 2 | Artyom Dzyuba | Group Stage | UEFA Champions League 19/20 |
| 2 | Sardar Azmoun | Group Stage | UEFA Champions League 19/20 |
| 2 | Oleg Shatov | Group Stage | UEFA Champions League 15/16 |
| 2 | Aleksandr Kerzhakov | Group Stage | UEFA Champions League 13/14 |
| 2 | Danny | Group Stage | UEFA Champions League 12/13 |
| 2 | Danny | Group Stage | UEFA Champions League 08/09 |
| 1 | Aleksey Sutormin | Group Stage | UEFA Champions League 21/22 |
| 1 | Magomed Ozdoyev | Group Stage | UEFA Champions League 21/22 |
| 1 | Daler Kuzyaev | Group Stage | UEFA Champions League 21/22 |
| 1 | Wendel | Group Stage | UEFA Champions League 21/22 |
| 1 | Yaroslav Rakitskiy | Group Stage | UEFA Champions League 21/22 |
| 1 | Artyom Dzyuba | Group Stage | UEFA Champions League 20/21 |
| 1 | Sebastian Driussi | Group Stage | UEFA Champions League 20/21 |
| 1 | Alexandr Yerokhin | Group Stage | UEFA Champions League 20/21 |
| 1 | Yaroslav Rakitskiy | Group Stage | UEFA Champions League 19/20 |
| 1 | Magomed Ozdoyev | Group Stage | UEFA Champions League 19/20 |
| 1 | Axel Witsel | Group Stage | UEFA Champions League 15/16 |
| 1 | Danny | Group Stage | UEFA Champions League 15/16 |
| 1 | Salomon Rondon | Group Stage | UEFA Champions League 14/15 |
| 1 | Danny | Group Stage | UEFA Champions League 14/15 |
| 1 | Axel Witsel | Group Stage | UEFA Champions League 14/15 |
| 1 | Hulk | Group Stage | UEFA Champions League 14/15 |
| 1 | Oleg Shatov | Round of 16 | UEFA Champions League 13/14 |
| 1 | Salomon Rondon | Round of 16 | UEFA Champions League 13/14 |
| 1 | Viktor Fayzulin | Group Stage | UEFA Champions League 12/13 |
| 1 | Roman Shirokov | Group Stage | UEFA Champions League 12/13 |
| 1 | Hulk | Group Stage | UEFA Champions League 12/13 |
| 1 | Aleksandr Kerzhakov | Group Stage | UEFA Champions League 12/13 |
| 1 | Sergei Semak | Round of 16 | UEFA Champions League 11/12 |
| 1 | Danny | Group Stage | UEFA Champions League 11/12 |
| 1 | Viktor Fayzulin | Group Stage | UEFA Champions League 11/12 |
| 1 | Konstantin Zyryanov | Group Stage | UEFA Champions League 11/12 |
| 1 | Nicolas Lombaerts | Group Stage | UEFA Champions League 11/12 |
| 1 | Fatih Tekke | Group Stage | UEFA Champions League 08/09 |
| 1 | Pavel Pogrebnyak | Group Stage | UEFA Champions League 08/09 |
