| 10 | Erling Haaland | Group Stage | UEFA Champions League 20/21 |
| 10 | Robert Lewandowski | Group Stage | UEFA Champions League 12/13 |
| 8 | Jan Koller | First Group Stage | UEFA Champions League 02/03 |
| 7 | Pierre-Emerick Aubameyang | Group Stage | UEFA Champions League 16/17 |
| 6 | Robert Lewandowski | Group Stage | UEFA Champions League 13/14 |
| 5 | Marco Reus | Group Stage | UEFA Champions League 13/14 |
| 4 | Jude Bellingham | Group Stage | UEFA Champions League 22/23 |
| 4 | Achraf Hakimi | Group Stage | UEFA Champions League 19/20 |
| 4 | Raphael Guerreiro | Group Stage | UEFA Champions League 18/19 |
| 4 | Pierre-Emerick Aubameyang | Group Stage | UEFA Champions League 17/18 |
| 4 | Marco Reus | Group Stage | UEFA Champions League 16/17 |
| 4 | Ciro Immobile | Group Stage | UEFA Champions League 14/15 |
| 4 | Marco Reus | Group Stage | UEFA Champions League 12/13 |
| 4 | Lars Ricken | Quarter-finals | UEFA Champions League 96/97 |
| 4 | Karlheinz Riedle | Quarter-finals | UEFA Champions League 96/97 |
| 4 | Stephane Chapuisat | Quarter-finals | UEFA Champions League 97/98 |
| 3 | Marco Reus | Group Stage | UEFA Champions League 21/22 |
| 3 | Erling Haaland | Group Stage | UEFA Champions League 21/22 |
| 3 | Donyell Malen | Group Stage | UEFA Champions League 21/22 |
| 3 | Shinji Kagawa | Group Stage | UEFA Champions League 16/17 |
| 3 | Marco Reus | Group Stage | UEFA Champions League 14/15 |
| 3 | Pierre-Emerick Aubameyang | Group Stage | UEFA Champions League 14/15 |
| 3 | Adrian Ramos | Group Stage | UEFA Champions League 14/15 |
| 3 | Heiko Herrlich | Group Stage | UEFA Champions League 96/97 |
| 3 | Stephane Chapuisat | Group Stage | UEFA Champions League 96/97 |
| 3 | Andreas Moller | Group Stage | UEFA Champions League 97/98 |
| 3 | Marcio Amoroso | First Group Stage | UEFA Champions League 02/03 |
| 3 | Fredi Bobic | First Group Stage | UEFA Champions League 99/00 |
| 2 | Karim Adeyemi | Group Stage | UEFA Champions League 22/23 |
| 2 | Raphael Guerreiro | Group Stage | UEFA Champions League 22/23 |
| 2 | Jadon Sancho | Group Stage | UEFA Champions League 20/21 |
| 2 | Julian Brandt | Group Stage | UEFA Champions League 19/20 |
| 2 | Jadon Sancho | Group Stage | UEFA Champions League 19/20 |
| 2 | Erling Haaland | Round of 16 | UEFA Champions League 19/20 |
| 2 | Ousmane Dembele | Group Stage | UEFA Champions League 16/17 |
| 2 | Niclas Fullkrug | Group Section | UEFA Champions League 23/24 |
| 2 | Julian Brandt | Group Section | UEFA Champions League 23/24 |
| 2 | Marco Reus | Group Section | UEFA Champions League 23/24 |
| 2 | Karim Adeyemi | Group Section | UEFA Champions League 23/24 |
| 2 | Henrikh Mkhitaryan | Group Stage | UEFA Champions League 13/14 |
| 2 | Mario Gotze | Group Stage | UEFA Champions League 12/13 |
| 2 | Felipe Santana | Round of 16 | UEFA Champions League 12/13 |
| 2 | Lars Ricken | Group Stage | UEFA Champions League 95/96 |
| 2 | Andreas Moller | Group Stage | UEFA Champions League 95/96 |
| 2 | Michael Zorc | Group Stage | UEFA Champions League 97/98 |
| 2 | Heiko Herrlich | Group Stage | UEFA Champions League 97/98 |
| 2 | Tomas Rosicky | First Group Stage | UEFA Champions League 02/03 |
| 2 | Torsten Frings | Second Group Stage | UEFA Champions League 02/03 |
| 2 | Jan Koller | First Group Stage | UEFA Champions League 01/02 |
| 2 | Marcio Amoroso | First Group Stage | UEFA Champions League 01/02 |
| 1 | Julian Brandt | Group Stage | UEFA Champions League 22/23 |
| 1 | Marco Reus | Group Stage | UEFA Champions League 22/23 |
| 1 | Thorgan Hazard | Group Stage | UEFA Champions League 22/23 |
| 1 | Jude Bellingham | Group Stage | UEFA Champions League 21/22 |
| 1 | Lukasz Piszczek | Group Stage | UEFA Champions League 20/21 |
| 1 | Jude Bellingham | Quarter-finals | UEFA Champions League 20/21 |
| 1 | Axel Witsel | Group Stage | UEFA Champions League 20/21 |
| 1 | Thorgan Hazard | Group Stage | UEFA Champions League 20/21 |
| 1 | Mahmoud Dahoud | Round of 16 | UEFA Champions League 20/21 |
| 1 | Raphael Guerreiro | Group Stage | UEFA Champions League 20/21 |
