| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Aaron Lennon | 34 | 25 | 9 | 9 | 9 | 3 |
Peter Crouch | 34 | 20 | 18 | 14 | 6 | 4 |
Luka Modric | 32 | 32 | - | - | 5 | 3 |
Benoit Assou-Ekotto | 30 | 30 | 2 | - | 4 | - |
Heurelho Gomes | 30 | 30 | 1 | - | - | - |
Gareth Bale | 30 | 29 | 1 | 1 | 4 | 7 |
Roman Pavlyuchenko | 29 | 18 | 18 | 11 | 13 | 9 |
Rafael van der Vaart | 28 | 28 | - | - | 15 | 13 |
William Gallas | 27 | 26 | 1 | 1 | 1 | - |
Michael Dawson | 24 | 24 | 1 | - | - | 1 |
Jermain Defoe | 22 | 16 | 8 | 6 | 7 | 4 |
Alan Hutton | 21 | 19 | 3 | 2 | 1 | 2 |
Younes Kaboul | 21 | 19 | 4 | 2 | 2 | 1 |
Wilson Palacios | 21 | 16 | 12 | 5 | 9 | - |
Jermaine Jenas | 19 | 14 | 17 | 5 | 2 | - |
Sandro | 19 | 11 | 16 | 8 | 2 | 1 |
Vedran Corluka | 15 | 13 | 16 | 2 | 3 | - |
Tom Huddlestone | 14 | 13 | 2 | 1 | 2 | 2 |
Niko Kranjcar | 13 | 2 | 29 | 11 | 1 | 2 |
Sebastien Bassong | 12 | 7 | 30 | 5 | 1 | 1 |
Carlo Cudicini | 8 | 8 | 25 | - | - | - |
Steven Pienaar | 8 | 5 | 6 | 3 | 4 | - |
Robbie Keane | 7 | 2 | 10 | 5 | 2 | - |
Ledley King | 6 | 6 | - | - | 1 | - |
Danny Rose | 4 | 4 | 5 | - | 2 | - |
Giovani Dos Santos | 3 | - | 4 | 3 | - | - |
David Bentley | 2 | 1 | 4 | 1 | - | - |
Kyle Walker | 1 | - | 1 | 1 | - | - |
Stipe Pletikosa | - | - | 12 | - | - | - |
Jonathan Woodgate | - | - | 2 | - | - | - |
Jake Livermore | - | - | 2 | - | - | - |
Bongani Khumalo | - | - | 3 | - | - | - |
Kyle Naughton | - | - | 1 | - | - | - |
Ben Alnwick | - | - | 2 | - | - | - |
John Bostock | - | - | 1 | - | - | - | 514 | 418 | 266 | 96 | 96 | 53 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .